9 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Wilsons, Pregnancy - AFLP ... AIH, Wilson's, HH ... kwburak #LFTs #Elevated ... Algorithm #diagnosis #hepatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... of Pregnancy (AFLP ... HELLP (Hemolysis, Elevated ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... Syndrome (Hemolysis, Elevated ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
HELLP (Hemolysis, Elevated ... Liver tests, Low ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... iMedEducation #AFLP ... Pregnancy #hepatology ... #obstetrics #obgyn ... #diagnosis #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
PBC, PSC, IgG4, HLH ... specificity to elevated ... ALP • AST/ALT ... > ALP: Typical ... diagnosis #algorithm #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Hemochromatosis HH ... with suspected HH ... transaminase; HH ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
>500 ng/mL • Elevated ... soluble CD25 • Elevated ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Hyperferritinemia - Elevated ... liver enzymes ... Elevated soluble ... #Hematology #HemeOnc