3898 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
K, Elevated phos ... , Elevated uric ... acid, Elevated Cr ... TLS #diagnosis #management ... #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
based on symptoms, elevated ... ≥45% and SF is elevated ... including liver and hematologic ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
>500 ng/mL • Elevated ... soluble CD25 • Elevated ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... Criteria: • Elevated ... PV #Diagnosis #Management ... Summary #treatment #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if WBC > 5 or elevated ... APML #diagnosis #management ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
fibrinogen • Elevated ... causes #treatment #management ... #hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated ... MatthewHoMD #Elevated ... INR #Algorithm #Hematology
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
Deficiency: MMA elevated ... , Homocysteine elevated ... , Homocysteine elevated ... VitaminB12 #diagnosis #hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... Syndrome #HES #Hematology ... eosinophils #diagnosis #management
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Time (PT) - Often Elevated ... (PTT) - Often elevated ... inhibitor Both elevated ... Thromboplastin #laboratory #hematology