47 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Elevated Transaminases ... Metabolic: Wilson Disease ... Vascular: Budd-chiari syndrome ... Transaminitis #Elevated ... Diagnosis #causes #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... → Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... thrombocythemia), Autoimmune disease ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... >500 ng/mL • Elevated ... • Bicytopenia Treatment ... #hematology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the Treatment ... Editor Note (from ophthalmology ... HCQ treatment would ... Even with macular disease ... #COVID19 #Pharmacology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Liver Failure - Elevated ... synthesis - Elevated ... chronic liver disease ... the hepatorenal syndrome ... LiverFailure #Hepatic #Hepatology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
(Mannitol) • Elevated ... intraocular pressure • Elevated ... disequilibrium syndrome ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Mild jaundice, Elevated ... necrosis HELLP Syndrome ... (Hemolysis, Elevated ... #Pregnancy #hepatology