69 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PT, aPTT(liver disease ... , ANA (e.g., SLE ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... #Causes #Workup
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Treatment: • ... #Summary #diagnosis ... #rheumatology # ... management
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
nodular thyroid disease ... Graves disease – ... Graves disease! ... Check pregnancy test ... AND management options
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... exclude inflammatory disease ... connective-tissue disease ... #Rheumatic #Disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... skin injury) • Neurologic ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
patients with anemia, diagnose ... disease with serology ... change medical management ... Gastrointestinal #Evaluation #workup ... #diagnosis #gastroenterology
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Presentation: • Mild disease ... Meningitis • Weil's Disease ... Severe pulmonary disease ... agglutination - test ... #treatment #management