34 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... thyroid function test ... (CVID, WAS), (neurologic ... #hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
and treatment can ... Inflammatory causes ... syndrome • Systemic lupus ... BEE #Syndromes #neurology ... #differential #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Erythematosus #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... #differential #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... joint • Systemic lupus ... (to support a diagnosis ... laboratory #workup #diagnosis
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Borrelia (Lyme Disease ... encephalitis, West ... - Systemic Lupus ... #Differential #Diagnosis ... #Causes #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Positive pathergy test ... is a skin prick test ... Arthritis, AS Treatment ... signs #symptoms #rheumatology