33 results
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... Schistosomiasis - Autoimmune ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... quadrant discomfort Signs ... disease (e.g. dryness ... disease, Persistent ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... Veno-occlusive disease ... #Diagnosis #causes ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... Hepatitis • Autoimmune ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
glomerulopathy, cirrhosis ... Chain deposition disease ... Atypical HUS, autoimmune ... #differential # ... hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Ischemia • Autoimmune ... • Cholestatic disease ... Infiltrative • Cirrhosis
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
dullness, puddle sign ... incisional). 3) Signs ... of underlying disease ... 3) Optional tests ... #Diagnosis #hepatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... diseases • In ... primary biliary cirrhosis ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... 65 years PBC Pathophysiology ... failure PBC Signs ... bile ducts Differential ... #workup #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Membrane): - Autoimmune ... Laboratory Tests ... #Diagnosis #hematology