21 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... /Symptoms Alopecia ... , Fever, Malar rash ... , Oral ulcers, Rash ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
scaly annular lesions ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes - THE ALGORITHMIC ... rashes but without signs ... have a broader differential ... #Algorithm #Central ... #Peripheral #Differential
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... with Systemic Lupus ... should have other symptoms ... like “butterfly rash
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... #Differential # ... Diagnosis #Algorithm
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... • Discoid lupus ... #skin #rashes #differential ... #diagnosis #rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... soles • Discoid Lupus
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... New-onset fever with rash ... #Dermatology #Rash ... #Differential #