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management algorithm causes lad lymphadenopathy chronic cll diffuse focal hodgkins leukemia lymphocytic anemia apml classification differentiation hemeonc mds myelodysplasia myelodysplastic
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
of Diffuse and Localized ... Inflammatory / Infectious ... Neoplastic (Leukemia, Lymphoma ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Anterior • Infection ... Axillary: • Infection ... (In absence of infection ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Rheumatoid Arthritis ... Pseudotumor - Infectious ... History of Bleeding, Infection ... #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Etiology: - Infections ... Diagnosis of B-Symptoms ... #oncology #diagnosis ... hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Pure red cell aplasia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Complications: 1) Infection ... to large cell lymphoma ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... ingestion • B symptoms ... Treatment • Early ... ABVD x 4 cycles + Localized ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
: >3 symptoms, or ... initiation • Differential ... Diagnosis: Infection ... #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... Causes • Anemia • Aplastic ... • Parvovirus infection ... #hematology #oncology
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