10 results
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... StanfordChiefs #ANCA ... #diagnosis #algorithm ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
antibodies) • Systemic ... Vasculitis: • ... + 60% • Eosinophilic ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... • EGPA: - Eosinophilia ... Differential Diagnosis ... purpura: strong sign ... #rheumatology #
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... Asthma Tugs (vasculitis ... Lymphomas - Systemic ... Mastocytosis - Acute ... #Causes #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... #Rheumatology
Cough - Diagnostic Schema

Infectious: URTI, LRTI, Bacterial, Viral
Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body
Airway Disease:
Bronchiectasis Other organ/systemic ... CHF, Autoimmune Vasculitis ... mycobacterial), Eosinophilic ... #Schema #Acute ... #Differential #Algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... clinical context and signs ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... Interstitial nephritis: eosinophilia
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Differential Diagnosis ... : • ANCA-associated ... Pleural effusions • Acute ... #Rheumatology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Impairment: • Acute ... central nervous system ... Lack of UMN/LMN signs ... ) ANCA titers, hepatitis
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
female, asian • Systemic ... hypergammaglobulinemia, ↑ acute ... phase reactants, eosinophilia ... No necrosis, No vasculitis ... workup #treatment #rheumatology