19 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... obstruction - Drug-Induced ... - Wilson disease ... #Differential #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... • Alcoholic hepatitis ... • Others #LFTs ... #Causes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... #algorithm #gastroenterology ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Drug Induced ... #Causes #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... , Recreational Drugs ... Differential #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... valproate, azoles), Drugs ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... for alternative causes ... disease, Hepatic ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... (AAH) Drug-Induced ... ) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... #gastroenterology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
calling a consult HPI ... - Vitals - LFTs ... disease work up ... Calling #Referral #Hepatology ... #Gastroenterology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Renal Disease, Liver ... Deficiency • Drugs ... #Causes #Hematology