11 results
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
primary OR secondary AI ... primary or secondary AI ... High = primary AI ... - Low = secondary ... or tertiary AI
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Polyglandular Autoimmune Syndrome ... #AI #Differential ... #Causes #endocrinology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Syndrome of Inappropriate ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology ... #Causes
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
specificity for AI ... > 15 excludes AI ... have diagnosed AI ... primary vs secondary AI ... #Stimulation #Endocrinology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Syndrome of Inappropriate ... • Reduced GFR, AKI ... #Hyponatremia #Nephrology ... #Causes
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
In secondary AI ... Hyperpigmentation is absent (low ... diagnostic of AI ... least 18 excludes AI ... diagnostic of AI
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Differential Diagnosis Algorithm ... Tea and Toast Syndrome ... Beer Potomania - Low ... Hypothyroidism, adrenal insufficiency ... #causes #nephrology
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
Infectious Causes ... of Adrenal Insufficiency ... Waterhouse-Friderichsen syndrome ... #AI #differential ... #diagnosis #endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... • Weakness • Low-grade ... /dL -> Primary AI ... ug/dL Primary AI ... addisons #disease #endocrinology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Hypothyroidism, Adrenal Insufficiency ... Cirrhosis, Nephrotic syndrome ... table #sodium #nephrology