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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... disorders #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL (Acute Lymphoblastic ... involvement CML ... ↓ LAP Score • CML ... lymphadenopathy CML
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... • Lymphoid (ALL ... • Lymphoid (CLL ... CD23, o CML ... Blood #Disorders #hematology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... Lymphoblastic Leukemia (ALL ... ) • Acute ... Myeloid Leukemia (CML
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Diagnosis Algorithm ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... #Nephrology #Causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... Adenoma, BAH, AME ... #nephrology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Malignancies (eg CML ... , ALL) • Solid ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... Transform to DLBCL, PML ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute ... myeloid leukemia (CML ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... myeloid leukemia (CML ... translocation • Acute ... thrombocythemia • Acute ... Diagnosis #causes #hematology