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diagnosis rheumatology differential vasculitis classification lupus algorithm ana antibodies antinuclear aortitis arthritis conditions cryoglobulinemia cryoglobulins disease druginduced erythematosus extrarticular joint
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... pathologically or clinically ... polyangiitis (GPA ... differential #diagnosis #algorithm ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... Genitourinary system ... Amyloidosis • Eosinophilic ... system • Mitral ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... bullous or vesicular eruption ... and branches • GCA ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
(GCA), Takayasu's ... Nodosa (PAN), ANCA ... (RA), Systemic ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Elevated ESR and CRP GCA ... develop in pts with GCA ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... months to years) Systemic ... #comparison #table ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... macular, patchy eruption ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... diseases: - 10% SLE ... DDX: • ANCA (Antineutrophil ... erythematosus (SLE
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... ACE level, CXR, ANCA ... and RF (if clinical ... diagnosis #testing #Rheumatology
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