12 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... restriction alone in SIADH ... Present (Uosm ≥100): SIADH ... , Renal Sodium loss ... #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Diagnosis Algorithm ... , SSRIs) - SIADH ... exclude: CKD, Thiazides ... #diagnosis #nephrology ... #sodium
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... Utilizing Uric Acid ADH ... Low Uric Acid → SIADH ... #nephrology #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... Hypovolaemia → ADH ... Pathophysiology #diagnosis #nephrology ... #hyponatremia # ... comparison
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... : • ADH ON (UOsm ... OFF (UNa > 30): SIADH ... salt wasting • ADH ... #sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... Euvolemic; no physiologic ... losses (especially thiazide ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... Euvolemic; no physiologic ... losses (especially thiazide ... #Nephrology #Differential
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
and Workup Step ... Repeat the sodium ... EUVOLEMIC • SIADH ... #Diagnosis #Workup ... #Algorithm #Nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... Another important physiological ... #hyponatremia #ADH ... EBV #potomania #SIADH ... #Thiazides #UNAa
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
Primary Polydipsia Physiology ... Pseudohyponatremia, SIADH ... intoxication Initial Workup ... , Urine Sodium ... diagnosis #management #nephrology