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diagnosis differential management rheumatology algorithm disease diseases neurology acute addisons adrenal aki ana anca antibody antineutrophil antinuclear associations autoantibodies cobalamin
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anti-SSB (La) - Sjogren's ... transglutaminase (TTG) - Celiac ... #rheumatology #antibodies
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... Glomerulonephritis • Anti-GBM antibodies ... lupus, sarcoid, Sjögren ... Diagnosis #Algorithm #Causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Antineutrophil #antibodies
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Vasculitis (lupus, RA, Sjogren's ... of antinuclear antibodies ... antineutrophil cytoplasmic antibodies ... Diagnosis #Algorithm #Causes
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... 21-Hydroxylase Antibodies ... insufficiency - Celiac ... 21-hydroxylase antibodies
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... Pernicious anaemia and Sjögren's ... Crohn 's disease, coeliac
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... enlargement Sjogren's ... hypofunction • Antibodies ... • Antinuclear antibodies ... Hypocomplementemia • Can cause
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Autoimmune: thyroid, Sjogren ... Labs: - AchR antibodies ... assay - MuSK antibodies ... - LRP4 antibodies ... Myasthenia Crises
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... for NMO, SLE or Sjogren's ... • Infectious causes ... Bechet disease - Sjogren ... Antiamphiphysin antibodies
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
diseases (mainly Sjogren ... The two antibodies ... transglutaminase antibodies ... anti-endomysial antibodies ... performed in select cases
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