21 results
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... thrombosis in cancer ... risk of recurrent VTE ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... ) and IMPROVE (VTE ... validated for VTE ... treatment, only ... Anticoagulation #Factors #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Treatment: • Consider ... diagnosis #management #treatment ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Classify severity Treatment ... by a hemophilia treatment ... center. ... Diagnosis #Management #treatment ... #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... ecchymoses, mucosal bleeding ... Treatment: ... #oncology #hematology