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erythematosus lupus sle vasculitis management patterns signs algorithm antinxp2 antinxp2dm arthritis autoantibodies autoimmune criteria disease disorders dm eularacr fungal hematology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Maheswaranathan @MithuRheum and ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... likely it will be clinically ... #Antibodies #ANA ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Diagnosis: • ANCA-associated ... Still disease, dermatomyositis ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... : - ANA 95-100% ... Diagnosis and Lupus ... #rheumatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
(DM) and Polymyositis ... : Pathogenesis and ... clinical findings ... Elevated Antinuclear ... Antibodies: Anti-Jo
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... least 2 joints • Neurologic ... low C4, Low C3 and ... Highly specific antibodies ... #diagnosis #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... untreated, Behave and ... response to treatment and ... #pathophysiology ... #Hematology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Diagnosis: Systemic ... Symptoms (Sx) in ... #diagnosis #rheumatology ... #classification
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... rash on the face ... papules Clinical ... #rheumatology # ... dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... rash (Gottron papules ... • Mechanic's hands ... • Conduction system ... #differential #
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