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diagnosis rheumatology erythematosus lupus sle management disorders ana antinuclear arteritis arthropathies arthropathy autoantibodies autoimmune behcet cord criteria disease eularacr gca
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #erythematosus ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... 69% - Malar rash ... autoantibodies #signs ... #symptoms #mimickers
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... Lupus Erythematosus ... should have other symptoms ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Skin Disease Classification ... permanent alopecia Differential ... Induced Lupus: • Symptoms ... 1, SCL-70, RNP antibodies
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Symptoms (Sx) in ... purpura: strong sign ... C-ANCA) pattern: antibodies ... #rheumatology #classification
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... likely it will be clinically ... rheumatology #diagnosis #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... cutaneous lupus • Arthritis ... least 2 joints • Neurologic ... Highly specific antibodies
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Symptoms (SX) in ... purpura: Strong sign ... ischemia • Skin: Erythematous ... , mucositis • Rash
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Diagnosis Algorithm ... pupil (AACG) • Systemic ... symptoms and signs ... ) • Temporal arteritis ... #neurology #PHANTOMS
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... skin injury) • Neurologic ... Behcet disease) Differential ... diagnosis #management #signs
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