13 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Fever, Arthralgia/arthritis ... , Skin rash ± odynophagia ... fraction < 20% Differential ... #diagnosis #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of hip (rare), Arthritis ... Demyelinating syndromes ... #erythematosus ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Classification: ... permanent alopecia Differential ... Clinical Features ... Induced Lupus: • Symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... ) Differential Diagnosis ... , AS Treatment: ... #diagnosis #management ... #signs #symptoms
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... Petechial or purpuric rash ... lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... Diagnosis: Systemic ... Symptoms (Sx) in ... purpura: strong sign ... #classification
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... - Rash: multiple ... Episcleritis Signs ... Treatment: - Systemic ... #diagnosis #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... extensive skin rash ... Resolution > 15 days Differentials ... : symptomatic treatment ... #dermatology #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... months to years) Systemic ... Lupus Erythematosus ... Evolution: Chronic disease ... #rheumatology #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... Symptoms (SX) in ... purpura: Strong sign ... ischemia • Skin: Erythematous ... , mucositis • Rash