50 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematosus) ... cutaneous lupus erythematosus ... (ACLE) • Erythematous ... • Erythematous ... lupus erythematosus
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... central nervous system ... drugs, malignomas, and ... - systemic ... lupus erythematosus
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... Interstitial lung disease ... C viruses. systemic ... lupus erythematosus ... #vasculitis #differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... lupus erythematosus ... ANCA-associated vasculitides ... BEE #Syndromes #neurology ... #inflammatory #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... #rheumatology #classification
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... , Vasculitis, Purpura ... pain (20%) Renal disease ... #erythematosus ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Diagnosis and Lupus ... #Lupus #Erythematosus ... autoantibodies #signs #symptoms
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Evolution: Chronic disease ... #Erythematosus
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Presentation (Pulmonary and ... symptomatology Differential ... Immune Complex: Systemic ... lupus erythematosus ... #diagnosis #nephrology