30 results
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Polycythemia (Erythrocytosis ... Smoking, Snoring Chronic ... Sleep Apnea • Chronic ... Pulmonary Disease ... Algorithm #Causes #Hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... Alcoholic liver disease ... > 2 • NASH, Chronic ... • Gilbert's syndrome ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
vein: Budd-chiari syndrome ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Tumor lysis syndrome ... more aggressive form ... #Leukemia #Hematology ... #Oncology #Diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Features: POEMS, AL ... Ig deposition disease ... Differential #Diagnosis #hematology ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Lymphomas • Other hematologic ... Malignancies (eg CML, ALL ... NonHodgkins #comparison #oncology ... #differential #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Adult form: Less ... thigh bones -> chronic ... Malnutrition • Wilson's disease ... Hyophosphatasia #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
hepatocytes; in chronic ... liver disease, ... suppression leads to chronic ... the hepatorenal syndrome ... LiverFailure #Hepatic #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... tests ↑ AST ↑ ALT ... Diagnosis #Management #Hematology ... #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... thrombophlebitis, pulmonary ... Diagnosis: • + Clinical ... Antiphospholipid syndrome ... #hematology