21 results
Erythropoiesis (RBC Production and Maturation)

Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
Erythropoiesis ( ... EricsMedicalLectures/ #Erythropoiesis
#Erythropoietin
#Erythropoietin
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
hemolysis, exogenous erythropoietin ... conditions that impair erythropoiesis
Exogenous Testosterone Side Effects
 • Mood disorder, Depression, Aggression
 • ↑ Erythropoiesis
 • Hypogonadism +/-BPH, prostate
Aggression • ↑ Erythropoiesis
Conversion - Epoetin alfa (Procrit®) to Darbepoetin alfa (Aranesp™)

#Epoetin #Darbepoetin #Erythropoietin #Conversion #Table #ESAs #Procrit #Aranesp
#Darbepoetin #Erythropoietin
Medications for the Management of Anemia

TREATMENT OF ANEMIA
 - Cyanocobalamin/B12
 - Erythropoietin/epoetin alfa
 - Darbepoetin alfa
Cyanocobalamin/B12 - Erythropoietin
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
simulation • Erythropoiesis
How to Dose Erythropoietin Stimulating Agents

Epoetin alfa (Epogen, Procrit) 
Epoetin alfa-epbx (Retacrit)
Darbepoeitin alfa (Aranesp)

#Erythropoietin #ESA #Dosing
How to Dose Erythropoietin ... (Aranesp) #Erythropoietin
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Positive - Low/Normal Erythropoietin ... Polycythemia Vera Erythropoietin
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
• Ineffective Erythropoiesis