11 results
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Estimating the Total ... Dose (TDD) of Insulin ... #dosing #estimation ... #pharmacology #endocrinology ... #diabetes #DM2
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... deficit: - Type I DM ... - Type II DM ... #dka #hhs #pathophysiology ... #comparison #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications Summary ... Table Insulin ... comparison #management #endocrinology ... #dm2
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... cells, triggering insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... • Increases insulin-mediated ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
The “twin cycles” of diabetes, first introduced by Roy Taylor in 2008.  
#fatty liver #fatty
diabetes #t2d #dm2 ... #insulin resistance ... #pathophysiology ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... and feet Excess Insulin ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology Summary ... glucose-dependent insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management Summary ... • Metabolic: Insulin ... malignancy Pathophysiology ... Acromegaloid): insulin ... Diagnosis #Management #Endocrinology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
BMI < 18.5 kg/m2 ... including diuretics, insulin ... parenteral -> Insulin ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs