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diabetes pharmacology management comparison dka dosing acromegaly agonists based diabeticketoacidosis diagnosis dpp4 fatty glp1 hyperglycemic hyperosmolar inhibitors ketoacidosis medications metformin
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Pathophysiology ... Hyperosmolar Syndrome (HHS ... Polydipsia #dka #hhs ... #pathophysiology ... #comparison #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
Estimating the Total ... including most 2 diabetics ... #dosing #estimation ... #pharmacology #endocrinology ... #diabetes #DM2
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... Insulin Lifestyle ... comparison #management #endocrinology ... #dm2
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... cells, triggering insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... • Increases insulin-mediated ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
The “twin cycles” of diabetes, first introduced by Roy Taylor in 2008. #fatty liver #fatty
twin cycles” of diabetes ... fatty pancreas #diabetes ... #t2d #dm2 #insulin ... resistance #pathophysiology ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology Summary ... glucose-dependent insulin ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
-> Stimulates Insulin ... will stimulate insulin ... This drug class has ... Pharmacology #Management #Diabetes ... #DM2 #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
and Management Summary ... • Metabolic: Insulin ... malignancy Pathophysiology ... Acromegaloid): insulin ... Diagnosis #Management #Endocrinology
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