44 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... • Immunologic Workup ... management of SLE • Evolution ... Management #Summary #rheumatology
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... Sickle Cell Crises Clinical ... Management #Diagnosis ... #Management #Hematology ... Manifestations #Workup
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... Scleroderma) Multi-system ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... signs #symptoms #diagnosis ... #rheumatology
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... parallel to lines of skin ... - Differential diagnosis ... Pityriasis #rosea #clinical ... #dermatology #photo
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... solid cancers • Systemic ... management #treatment #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... characterized by a systemic ... Skin rash and malaise ... #Diagnosis #Clinical ... #Photo #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... Petechial or purpuric rash ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology