16 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... #APML #diagnosis
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... indicate preferred treatment ... limitation, further evaluation ... #Management #Pulmonary
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology # ... rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... progression to AML ... Immunosuppressive treatment ... #diagnosis #hematology
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Rituximab Evolution ... arterioles - Treatment ... David #Susac #Syndrome ... Diagnosis #Management #Rheumatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... cirrhosis • Intra-pulmonary ... perfusion scanning or pulmonary ... ) on room air Treatment ... hepatopulmonary #syndrome
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... dyskinesia • Young syndrome ... • Pulmonary artery ... • HRCT (high-resolution ... mycobacteria Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... workup #oncology #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
→ no immediate treatment ... after CRS) - Treatment ... : - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... Torsemide) • Acute pulmonary ... and nephrotic syndrome ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology