75 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... Clinical Manifestations ... Management #Diagnosis ... #Management #Hematology ... #SickleCell #Complications
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
Diagnosis of active ... Oncology #HemeOnc #Hematology ... Hypercalcemia #Anemia #Clinical ... #Diagnosis
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
normal factor activity ... 50% of normal activity ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... #differential #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... other orthopedic complications ... #differential #diagnosis ... #causes #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH) Clinical ... d-dimer, ↓ NK cell activity ... IL-2 receptor Diagnostic ... fibrinogen • ↓ NK activity ... #hematology #criteria
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
phases with their endogenous ... clot #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... unnecessary and cause ... the deadliest complication ... Transfusion #Thresholds #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Individual factor activity ... Serious: 100% factor activity ... Moderate: 50% factor activity ... Management #treatment #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura Activity ... factor-cleaving protease activity ... for this enzyme activity ... is the diagnostic ... #Workup #Hematology