137 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... thyroiditis that causes ... ‘Leakage’ symptoms ... Endocrinology #Diagnosis ... #Pathophysiology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in macrophages Diagnosis ... ß-glucocerebrosidase activity ... in GBA1 gene Clinical ... #Signs #Symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... #diagnosis #comparison
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... #differential #diagnosis
Hordeolum vs Chalazion

Hordeolum (Stye):
 • Location: Most commonly found at or near an eyelash follicle
 •
eyelash follicle • Cause ... of the lids • Symptoms ... upper lid • Cause ... eyedrops, surgery #Clinical ... #Diagnosis #Management
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... improvement in symptoms ... endpoint of all-cause
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Individual factor activity ... by a hemophilia treatment ... #Management #treatment ... #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Treatment: • Global ... IBS Symptoms: ... Rifaximin- up to 3 courses ... Secretagogues → activate ... gastroenterology #treatment