54 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... disordersDiagnosis ... #HES #Hematology ... #eosinophils #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
• Has a UGT1A1 activity ... as jaundice on clinical ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Mucous Membrane Disorder ... - Differential Diagnosis ... Stevens-Johnson Syndrome ... MucousMembranes #dermatology ... #Algorithm #causes
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #Causes #hematology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... - Differential Diagnosis ... McCune Albright syndrome ... #skin #dermatology ... #Algorithm #causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • They can cause ... Cryoglobulins Cause ... : • Clinical triad ... Labs/Diagnosis:
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
- Differential Diagnosis ... DM (visit 2), Diagnosis ... based on repeat clinic ... Steroids (Cushing's, exogenous ... HTN #Secondary #Nephrology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... lymphoproliferative disorders ... #hematology #anemia