61 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... differential #diagnosis #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
of dopaminergic activity ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
How to use it in clinical ... Characterizing activity ... pathway in the clinic ... understanding of pathophysiology ... signature #diagnosis #management
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
organic acids and bases ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... extrapulmonary cases ... Clinical Signs ... signs/symptoms of active ... decreased reflexes Pathophysiology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Active: Symptomatic ... Tuberculosis: • Endogenous ... characteristic features Clinical ... TB #Diagnosis #Management
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... exposure to allergen causes ... harmful -> Th Cells activate ... Allergy #Immunology #pathophysiology
For my UME micro course, I made a figure that captures this terminology and lets learners
the spectrum of clinically ... important drug classes ... does not equal clinical ... #antibiogram #pharmacology ... #management #spectrum
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
hospitalization) • Pathophysiology ... Risk Factors • Clinical ... Presentation • Management ... #criticalcare #pharmacology ... #management
Pearls for Treatment of Alcohol Use Disorder

First-line pharmacotherapies for moderate to severe AUD include naltrexone and
abdominal pain, nausea ... cirrhosis or who are actively ... #UseDisorder #Management ... #Medications #Pharmacology