12 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Proteinuria often ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... • Drugs Glomerular ... albuminuria) - Active ... #Nephrology #Differential
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... Brown urine - Proteinuria ... • Nutcracker syndrome ... #urology #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... proteinuria. ... hemolytic-uremic syndrome ... Nephrocalcinosis causes ... #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Mesangiocapillary GN • Active ... , +/- proteinuria ... formation along glomerular ... anti-phospholipid syndrome ... Glomerulonephritis #MPGN #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... of glomerular disease ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... #glomerular #disease ... initial #testing #nephrology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
based on repeat clinic ... • Nephritic syndrome ... Excess: • Conn's syndrome ... Steroids (Cushing's, exogenous ... HTN #Secondary #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively ... #nephrology