12 results
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
be the primary cause ... - Glomerular hyperfiltration ... - Cytokines #Pathophysiology ... #Nephrology #CKD
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... albuminuria) - Active ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Functions - Glomerulus ... - Formation of glomerular ... organic acids and bases ... tubule (DCT) - Active ... Segments #Function #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
intoxication Cause ... inversely related to glomerular ... rate by tubulo-glomerular ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... why LR does not cause ... differential #diagnosis #pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... of glomerular disease ... nephrotic #nephritic #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Mesangiocapillary GN • Active ... dysmorphic RBC, RBC casts ... formation along glomerular ... Glomerulonephritis #MPGN #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively ... #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... #glomerular #disease ... initial #testing #nephrology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... - Causes progressive ... by decreasing activity ... Lateral #Sclerosis #neurology