6 results
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Neutrophilic dermatoses ... - Rash: multiple ... Causes: - Idiopathic ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... manifestations: from easy bruising ... Petechial or purpuric rash ... MAS #Macrophage #Activation ... #Management #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... Willebrand factor activity ... ristocetin cofactor activity ... von Willebrand syndrome ... discern these causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... PLT: Petechiae, bruising ... develop leukostasis syndrome ... • Tumor lysis syndrome
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... Dystrophy Heme: • ↓ activity ... Inflammation → Macrophage activation ... Hepatomegaly: Bruising
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... activation of the ... Syndrome) 3. ... absent NK-cell activity ... Diagnosis #Management #Hematology