24 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Symptoms: • The ... Edema in 70% of cases ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... survival is 93-95% Pathophysiology ... increased B-cell activity ... #Management #Signs
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... and Management ... Rifaximin- up to 3 courses ... Secretagogues → activate ... #Diagnosis #Management
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... decr release and activity ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... Clinical Signs/Symptoms ... - Erosions and crusts ... #Management #dermatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Tuberculosis - Diagnosis ... and Management ... extrapulmonary cases ... of active pulmonary ... decreased reflexes Pathophysiology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... development of skin symptoms ... Causes: - Idiopathic ... #diagnosis #dermatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Prevalence: 1-2 cases ... Pathophysiology ... continuous motor unit activity ... #Management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... Differentiation #Syndrome ... #management #hematology