16 results
Anemia - Workup and Differential Diagnosis
 - History, Physical Exam, Labs
 - Microcytic
 - Normocytic
 -
Anemia - Workup ... Normocytic - Macrocytic ... - Hemolytic # ... Anemia #Workup # ... #causes
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential ... anemia (TTP, HUS ... #Anemia #Differential ... Diagnosis #Algorithm #causes
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Bleed • Hemolysis ... #Differential # ... #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... , exogenous erythropoietin ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Lead poisoning • Macrocytic ... spherocytosis, Hemolytic ... thrombocytopenia (ITP ... key #diagnosis #differential ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... thrombocytopenic purpura (TTP ... #differential # ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... anemia • ... • MAHA (TTP ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... thrombocytopenia - DIC, TTP ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... anemia Indirect ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology