9 results
diagnosis toxicology management nephrology aspirin colchicine differential salicylate agitation anticoagulation causes citrate criticalcare delirium framework hyperphosphatemia icu infusion metabolic pad
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Phosphate Load: • Exogenous ... laxatives, Vitamin D toxicity ... Fosphenytoin • Endogenous ... Shift: • Lactic acidosis
Colchicine Toxicity Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly] 2-24 hrs • Severe GI distress
Colchicine Toxicity ... Naturally-occurring plant alkaloid ... • Metabolic acidosis ... #Colchicine #Toxicity
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
Salicylate Toxicity ... anion-gap metabolic acidosis ... Anion-Gap Metabolic Acidosis ... , Respiratory Alkalosis ... Salicylate #Aspirin #Toxicity
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic Alkalosis ... /L • Gastric alkalosis ... chronic respiratory acidosis ... ectopic ACTH) • Exogenous ... #Metabolic #Alkalosis
Salicylate Poisoning - Toxicology Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Toxicology Acute toxicity ... mixed respiratory alkalosis ... and metabolic acidosis ... Chronic toxicity ... #Toxicology #Pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
syndrome (PRIS) - acidosis ... glycol (solvent) toxicity ... result in lactic acidosis ... No pharmacologic ... (Haldol) - No pharmacologic
Propofol-Related Infusion Syndrome (PRIS) Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
• Metabolic acidosis ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Citrate Anticoagulation Toxicity Hypernatremia (HyperNa): - Citrate solutions may have ↑ sodium content and should be paired
Anticoagulation Toxicity ... think citrate toxicity ... Anion-Gap Metabolic Acidosis ... metabolism Metabolic alkalosis ... Anticoagulation #Toxicity
Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Metabolic: Metabolic acidosis ... #Colchicine #Toxicity ... Toxicology #Phases #Pharmacology
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