26 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... Diagnosis Framework ... should be based on clinical ... required until immune ... #AIDS #opportunistic
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... infection, HIV infection ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... classification #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Campylobacter jejuni - HIV ... #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... noncompliance • Clinical ... initiation Clinical
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... Diagnosis: MRI ... syndrome of HAD ... disorder #dementia #AIDS ... #Neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... - HIVImmune ... immunodeficiency virus (HIV ... #diagnosis #management
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes Immune-mediated ... important, as early diagnosis ... pachymeningitis • HIV ... MRI lesions and clinical ... #neurology #noninflammatory
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... accumulation of clinical ... treatment #summary #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... : 2 hit mechanism ... transfusion • Pathophysiology ... #diagnosis #comparison
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Lymphocytopenia DIAGNOSTIC ... primary or secondary immune ... chemotherapy) • Genetic syndromes ... • Infections - HIV ... #hematology #Differential