10 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... exposure to allergen causes ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... than 1500 and clinical ... eosinophilia Secondary Causes ... Malignancy - Immunologic
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Virologic and immunologic ... noncompliance • Clinical ... initiation Clinical ... #Inflammatory #Syndrome
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... /aggregate) of CD4 ... salivary ducts Clinical ... #Rheumatology #
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... ingestion and most cases ... diagnosis - History ... #Pathophysiology ... #Psychiatry #Diagnosis
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Pathogenesis and clinical ... weapon that can cause ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
CD can be associated ... mainly Sjogren’s syndrome ... and William’s syndromes ... the rash is an immunologic ... test for whom clinical