20 results
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Exogenous antigen ... associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology ... #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Anterior Cord Syndrome ... • Central Cord Syndrome ... Posterior Cord Syndrome ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... -> Particular CD4 ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... auto-reactive B and CD ... cells -> Tissue injury ... Pancarditis and valvular injury ... RheumaticFever #pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... and activating cellular ... causes direct injury ... PolyarteritisNodosa #Pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... glucose for use in cellular ... and acute kidney injury ... presentation - Clinical
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Reconstitution Inflammatory Syndrome ... (IRIS) - Pathophysiology ... factors: - Low CD4 ... pathogen-specific cellular ... #Inflammatory #Syndrome
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... quantify renal injury ... coagulopathy) • CBC ... hypercellular glomeruli, & cellular
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Guillain-Barré syndrome ... Direct muscle injury ... Risk of muscle injury ... IU/I • SAMS clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... EBV) • Others: Cellular