109 results
Alzheimer's Disease - Summary
 • Epidemiology
 • Pathophysiology
 • Risk Factors
 • Presentation
 • Diagnosis
 •
Alzheimer's Disease ... • Pathophysiology ... Treatment • Clinical ... #Summary #diagnosis ... #management #geriatrics
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... Diagnosis: • ... cells can indicate disease ... • Richter’s Syndrome
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... #Management #Summary
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Cr >2 mg/dL or CC ... Causes of false- ... diseases, CML, ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver disease ... Multiple myeloma, CML ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Summary myelo ( ... old, ~10,000 new cases ... Allogeneic stem cell ... Myelodysplastic #Syndrome
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... #management #treatment ... #summary #rheumatology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
- Differential Diagnosis ... DM (visit 2), Diagnosis ... based on repeat clinic ... Renal Parenchymal Diseases ... Steroids (Cushing's, exogenous
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... of Fever CRITICAL ... seizure - Sickle cell ... disease - Transplant ... Noninfectious #Causes
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
and Management ... Summary Clinical ... demineralization) • Renal disease ... plasma clonal cell ... is also >100 CMC