12 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
ALP - Biliary ... Transaminase >> Alkaline ... Cholestatic Pattern - Alkaline ... Transaminitis #diagnosis ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Highest • Bone • Liver ... - Drugs - Primary ... biliary Cholangitis ... #Algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
, lungs, RBCs Alkaline ... , biliary epithelium ... Conjugated/DBili) - Biliary ... Interpretation #diagnosis ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... dryness of the eyes ... Elevated ALP 2. ... Liver biopsy findings ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... PBC Labs: • Alkaline ... obstruction • ALP ... or higher • Liver ... #workup #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
, Alkaline Phosphatase ... : primarily within ... liver Alkaline ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
Algorithm for the Diagnosis ... of Primary Biliary ... cholangiopancreatography; ALP ... , alkaline phosphatase ... #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Areas of diagnostic ... include extrahepatic biliary ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... Abnormal #Algorithm #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... • Elevation of urinary ... Hyophosphatasia #hepatology ... #diagnosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... to multi-focal biliary ... asymptomatic at diagnosis ... disease management ... #Hepatology