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syndrome dermatology disease adultonset aosd differential oncology pulmonary abscess activation adult antinxp2 antinxp2dm apml bronchiectasis causes classification clinical dermatomyositis differentiation
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... #Disease #diagnosis ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
38 degrees • Chills ... Blood cultures • CXR ... early disease) • CXR ... pneumonectomy if fail ... #treatment #diagnosis
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... is often on the chest ... Treatment - Mild ... #rheumatology # ... management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... acid, Elevated Cr ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... 5 or elevated Cr ... common • Imaging: CXR ... Renal Failure Treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... +, Adult-onset Still ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
but typically fail ... Serum Copper • Chest ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involve anterior chest ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
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