26 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... Thyroid, Autoimmune ... ANA #patterns #rheumatology ... #diagnosis #differential
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diagnosis Congenital ... Diseases: • GATA2 ... Inflammatory and Autoimmune ... lupus erythematosus ... #Diagnosis #Hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Diagnosis and Lupus ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
- Diagnosis Algorithm ... suspected: • Signs ... and symptoms of ... microscopic colitis Differential ... • Autoimmune
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
conjunction with symptoms ... an underlying autoimmune ... syndrome • Systemic lupus ... #inflammatory #differential ... #diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... formation, systemic autoimmune ... with Systemic Lupus ... should have other symptoms
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Chain deposition disease ... Atypical HUS, autoimmune ... S - Systemic Lupus ... CHAMPS #Mnemonic #diagnosis ... #differential #
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... disease characterized ... elbows/wrists and knees ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... diseases • In ... RA) or systemic lupus ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... idiopathic) - Autoimmune ... Extravascular #Causes #differential ... #diagnosis #hematology