13 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... Dystrophy • Statin ... Diagnosis #Algorithm #Causes
Drugs associated with worsening of Myasthenia Gravis (MG):
•	D-penicillamine 
•	Botulinum toxin.
•	Telithromycin
•	Fluoroquinolones 
•	Quinine
•	Magnesium
•	Macrolide antibiotics 
•	Corticosteroids (may cause transient
with worsening of Myasthenia ... Corticosteroids (may cause ... Beta-blockers • Statins ... prevent prolonged myasthenic ... higher risk of myasthenic
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... Overview Myasthenia ... crises”. ... Imaging - CT Chest ... Crises - Severe
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... neurologic disease • Myasthenia ... Hydroxychoroquine - Statins ... #differential #causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Eaton Syndrome, Myasthenia ... poisoning, Scorpion sting ... Neuromuscular #Weakness #Causes
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Myopathy: Drugs (statin ... NMJ disorder (Myasthenia ... Differential #Diagnosis #causes
Trypanosoma cruzi Reactivation in the Brain- ...Magnetic resonance images of the brain showed a mass measuring
on T2-weighted imaging ... on T1-weighted imaging ... kinetoplasts (masses ... #clinical #NEJM
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
after Congo red staining ... well-recognized cause ... AL #lightchain #NEJM
Causes of Myocarditis 
1. Infectious Myocarditis
 • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
Causes of Myocarditis ... polymyositis, myasthenia ... more commonly cause ... Miscellaneous - Scorpion sting ... #Myocarditis #Causes
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... Hypovolemia: Asthenia ... year • Discuss spacing ... of IVIg cures