29 results
diagnosis oncology hemophagocytic hlh lymphohistiocytosis blood disease hemeonc induced mds myelodysplastic product reactions thrombocytopenia activation amiodarone anemia aplastic apml arteritis
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... eosinophils #diagnosis #management ... #algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... → Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Management of adult IgA Vasculitis (Henoch-Schönlein purpura) - Treatment algorithm for the management of IgAV patients
Henoch-Schönlein purpura) - Treatment ... algorithm for the ... Treatment remains ... #Treatment #Rheumatology ... #Vasculitis #Algorithm
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Unknown cause Treatment ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Pulm: Hypoxia, dyspnea ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Differential Diagnosis: Infection ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... • Platypnea - Dyspnea ... on radioactive lung ... #treatment #hepatology
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