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clinical ultrasound diagnosis hematology ocular coagulation differential echocardiogram lung cardiology pt causes disseminated hemorrhage intravascular pulmonary s4c aaa abdominal abnormal
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... Prolonged PT and aPTT ... intravascular coagulation (DIC
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... , FVII, FIX, FX ... intravascularcoagulation (DIC ... #Abnormal #PT #aPTT
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Thromboplastin Time (PTT ... warfarin) • Factor VII ... Thromboplastin Time (PTT ... elevated in: • DIC ... thematttsai #PT #PTT
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation (DIC ... • Prolonged PT/PTT ... levels of factors VII ... PT/INR: ↑ • PTT ... INR < 2.3 - APTT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
NORMAL PT/NORMAL PTT ... evaluation of factor VII ... Inherited: • Factor VII ... Warfarin • Acute DIC ... disease • Acute DIC
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation (DIC ... aggregation PT, aPTT ... small vessels #DIC
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
thromboplastin time (PTT ... decompensated DIC ... Diagnosis #Honc #DIC
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
complexes with FVIIa ... TF-FVIIa also activates ... thrombin #clot #PT #PTT
Pediatric Skull Fracture with Associated Hematoma on POCUS Working with the challenges of risk stratification, management of
Associated Hematoma on POCUS ... setting, where skull pocus ... Tough decisions: dc ... Fracture #Hematoma #POCUS
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 Comparison of Ocular Pathologies on POCUS: • Vitreous Detachment • Vitreous Hemorrhage • Retinal Detachment Vitreous detachment
Pathologies on POCUS ... tethers to the optic disc ... EUSmkh #Ocular #POCUS
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