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diagnosis hematology differential management prolonged pt aptt bruising classification petechiae treatment anemia arterial blanching bruise cascade crisis criticalcare cryofibrinogenemia dic
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Congenital • Factor ... Deficiency • Factor ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PT (INR) - Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... factor == NORMAL ... intravascular coagulation ... discern these causes ... Differential #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Jcortesizaguirr #Abnormal ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... amyloidosis #Abnormal ... #differential #hematology ... #coagulation
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... study (aPTT may be normal ... in mild cases) ... antigen (vWF:Ag) are normal ... Management #treatment #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... Complete blood count coagulation ... #Causes #dermatology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... Initiation phase caused ... , resulting in coagulation ... diagnosis #models #hematology ... #pathophysiology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... are typical of coagulation ... factor deficiencies ... Von Willebrand factor ... Measurement of coagulation
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