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diagnosis rheumatology causes coagulation hepatology management antiphospholipid apls aptt arthritis biliary cholangitis cirrhosis cppd dermatology dic differential disease disseminated druginduced
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... Plasma → Recheck abnormal ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... production of clotting factors ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis ... #Testing
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Consumption of Clotting Factors ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... - APTT < 1.5 x normal ... treatment #management #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Thrombocytopenia - Abnormal ... deficiency - Abnormal ... deficiency Work ... #Causes #dermatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... • Immunologic Workup ... druginduced #lupus #sle #comparison ... #table #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Rheumatoid factor ... more time for the laboratory ... #workup #diagnosis ... #testing #Rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... von Willebrand factor-cleaving ... levels - Usually normal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... Proximal limb muscle wasting ... • ALT & AST normal ... cholangitis #diagnosis #workup ... #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... colony stimulating factor ... Workup: • Complete ... cyclosporine) • Growth factors ... Syndromes #diagnosis #hematology
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