7 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Review of the Coagulation ... Contemporary Model ... , resulting in coagulation ... EricsMedicalLectures/ #Coagulation ... #hematology #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... treatment #management #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... generated by Tissue Factor ... #Coagulation #Cascade ... PTT #diagnosis #models ... #hematology #pathophysiology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... deficiency Work ... Complete blood count coagulation ... Differential #Diagnosis #Algorithm ... #Causes #dermatology
Acute-phase Reactants Synthesized in the Liver 
Positive acute-phase reactants (concentrations increase with acute inflammation)
 - Immune-related
Ceruloplasmin - Coagulation ... factors - ... Fibrinogen - Factor ... #pathophysiology ... #Laboratory
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
glands, lymph nodes ... relapse No specific laboratory ... antibodies, rheumatoid factor ... management #phenotypes #workup ... #treatment #rheumatology