85 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Pathogenesis and risk factors ... IBD • Chronic liver ... • Lifestyle Factors ... #Osteoporosis #pathophysiology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Cholangitis #pathophysiology ... psc #hepatology #comparison
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... could be multiple factors ... Decreased factor ... • Reduced liver ... Causes #diagnosis #differential
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
and Bleeding in Liver ... von Willebrand factor ... Generation • Incr Factor ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... deficiency • Liver ... the PTT suggests liver ... Acquired: • Liver ... Bruising #Hemostasis #Differential
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Decreased factor ... Reduced liver synthesis ... Factor consumption ... Causes #diagnosis #differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Acquired Risk Factors ... Syndrome, Ischemic Liver ... Venous #Arterial #pathophysiology ... #hematology #differential
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Deficiency of Factor ... Deficiency of Factor ... ) • Advanced Liver ... Autoimmune • Factor ... Summary #table #comparison
Liver Mass Differential Diagnosis
Solid:
 • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 •
Liver Mass Differential ... Cystadenoma, Polycystic liver ... Echinococcus #Liver ... #Mass #Differential ... Diagnosis #hepatology #Radiology
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
(+) Rheumatoid Factor ... Inflammatory disorders of Liver ... #Rheumatoid #Factor ... rheumatology #laboratory #differential